Research Pipeline
Discovery
Perform whole-genome sequencing (WGS) analysis of clinic families
Validation
Follow cancer rates in adult zebrafish carrying novel patient mutations
Characterization
Apply integrative, unbiased tools to characterize mechanism and interrogate novel pathway in the context of pancreas development
Translation
Assess preventative and therapeutic potential of novel pathway in pre-clinical studies
Located in the heart
of Harvard Medical School and Boston’s biomedical research community
Sahar Nissim, MD, PhD
A physician-scientist with interests in cancer biology and pancreatic development, Dr. Nissim is dedicated to uncovering the mechanisms of previously uncharacterized mutations leading to pancreatic cancer. His research lab utilizes the zebrafish model to ask questions about molecular interactions and inter-generational disease, uncovering novel findings that lead to pre-clinical and clinical trials to treat pancreatic cancer. A longtime Boston resident, Dr. Nissim has chosen Harvard/BWH/DFCI to launch his lab and mentor the next generation of researchers.